William Dupps Laboratory

William Dupps, MD, PhD

Staff, Opthalmology
Joint Staff, Biomedical Engineering
Location: Cleveland Clinic Main Campus

Research

Dr. Dupps leads an interdisciplinary research team in the Ocular Biomechanics and Imaging Laboratory at the Cole Eye Institute focused on the biomechanics of keratoconus and methods for improving refractive surgery outcomes with patient-specific computational modeling.

Laboratory goals:

• Simulation-based diagnosis and treatment of corneal disease
• Computational modeling
• Elasticity imaging and corneal biomechanics

Biography

William J. Dupps Jr., MD, MS, PhD, a native of Catawba Island, Ohio, joined the staff of Cleveland Clinic in 2006 and has appointments in Ophthalmology, Biomedical Engineering and Transplantation. His academic appointments include Professor of Ophthalmology at the Cleveland Clinic Lerner College of Medicine and Professor of Biomedical Engineering at Case Western Reserve University. After graduating with an undergraduate degree in chemical Engineering from Purdue University, he completed his master’s and doctoral degrees in Biomedical Engineering at The Ohio State University, where he also earned his medical degree with honors as a fellow in the Medical Scientist Training Program. He completed an ophthalmology residency at the University of Iowa Department of Ophthalmology and Visual Sciences, a research fellowship in ocular gene therapy at the National Eye Institute, and a two-year Cornea and Refractive Surgery Fellowship at the Cole Eye Institute. He specializes in refractive surgery, corneal transplantation, and cataract surgery.

With research support from sources such as the National Keratoconus Foundation, the National Institutes of Health, and Research to Prevent Blindness, Dr. Dupps leads an interdisciplinary research team in the Ocular Biomechanics and Imaging Laboratory at the Cole Eye Institute focused on the biomechanics of keratoconus and methods for improving refractive surgery outcomes with patient-specific computational modeling. Dr. Dupps is listed in Who’s Who in Medicine and Healthcare, Who’s Who in Science and Engineering, and America’s Top Ophthalmologists. His contributions have been recognized by his peers through membership in the American Ophthalmological Society and honors such as the Kritzinger Award and a Senior Achievement Award from the International Society of Refractive Surgery and the American Academy of Ophthalmology.  He was named Teacher of the Year by the residents of the Cole Eye Institute in 2010 and is the Director of Cole Eye Institute’s cornea and refractive surgery fellowship training program.

Dr. Dupps is Editor of the Journal of Cataract & Refractive Surgery, a leading journal in the field of anterior segment eye surgery, and has authored numerous journal articles and book chapters. He is named on several patents and received the Cleveland Clinic’s first Early Career Innovation Award in 2008.

Education & Professional Highlights

Fellowship - Cleveland Clinic
Cornea & Refractive Surgery
Cleveland, OH USA
2006

Residency - University of Iowa College of Medicine
Ophthalmology
Iowa City, IA USA
2004

Internship - Indiana University School of Medicine
Transitional Medicine
Indianapolis, IN USA
2001

Medical Education - The Ohio State University College of Medicine and Public Health
Columbus, OH USA
2000

Medical Education - The Ohio State University College of Medicine and Public Health
Biomedical Engineering
Columbus, OH USA
1998

Graduate School - The Ohio State University
Biomedical Engineering
Columbus, OH USA
1995

Undergraduate - Purdue University
Chemical Engineering
West Lafayette, IN USA
1992

• Editor, Journal of Cataract & Refractive Surgery
• Principle Site Investigator, NIH/NEI Multi-Center Genetic Study of Fuchs’ Dystrophy   
• Research to Prevent Blindness Career Development Award
• NIH K12/KL2 Multidisciplinary Clinical Research Career Development Programs Grant
• Cleveland Clinic Foundation Innovations Grants
• Oral Examiner, American Board of Ophthalmology
• American Academy of Ophthalmology: Practicing Ophthalmologist Curriculum (POC) Refractive Management/Intervention Panel & Committee for Research, Regulatory & External Scientific Relations

• Ophthalmology

• Corneal transplantation & cataract
• Refractive surgery

• Omicron Delta Kappa National Leadership Honor Society
• S.J. Roessler Memorial Research Scholarship Award
• Landacre Society Research Honorary
• Latin American Studies Program Grant
• American Medical Student Association International Health Travel Grant
• Graduate Student Alumni Research Award, The Ohio State University
• Presidential Fellowship, The Ohio State University Graduate School
• Alpha Omega Alpha Honor Medical Society
• Phi Kappa Phi
• The Nation’s Deans List
• Eli Alcorn Prize in Ophthalmology, The Ohio State University
• National Eye Institute Travel Grant, ARVO
• The Fischbach Medical Scholarship, Delta Tau Delta Education Foundation
• Marquis Who’s Who in Medicine and Healthcare
• Cleveland Clinic Innovator Award
• Marquis Who’s Who in Science and Engineering
• America’s Top Ophthalmologists, Consumers’ Research Council of America
• Academic Hall of Fame, Port Clinton High School, Port Clinton, Ohio
• Early Career Innovation Award, Cleveland Clinic
• Distinguished Alumni Lecture, University of Iowa Department of Ophthalmology & Visual Sciences
• Best Doctors in America, Best Doctors Inc.
• Teacher of the Year, Cole Eye Institute, Cleveland Clinic
• Distinguished Alumnus Award, College of Engineering, The Ohio State University
• Cambridge Who’s Who Registry among Executives, Professionals and Entrepreneurs
• Cleveland’s Top Doctors, Cleveland Magazine
• Achievement Award, American Academy of Ophthalmology

• Roberts C, Dupps WJ, Katsube N. “Methods and instruments for refractive ophthalmic surgery.” US Patent 20030208190. Licensed by Bausch & Lomb Surgical. Published Nov. 3, 2003
• Roberts C, Dupps WJ, Katsube N. “System for refractive ophthalmic surgery.” European Patent Office 05013025.1
• Dupps WJ, Rollins AM, Ford M. Method for measuring biomechanical properties in an eye. Patent filed May 2006, issued May 3, 2011 as US 7935058 B2
• Krueger RR, Dupps WJ, Trokel SL, Thornton IL. Method for altering optic nerve head and scleral stiffness. US Provisional Patent Application No. 60/921,317, filed on April 2, 2007
• Dupps WJ, Sinha Roy A. Computational model of the eye. US Provisional Patent Application 61047179 filed April 23, 2008

• Association for Research in Vision and Ophthalmology, Cornea Section
• American Academy of Ophthalmology
• International Society of Refractive Surgery
• American Society of Cataract and Refractive Surgery
• International Society of Optical Engineering (SPIE)
• Cleveland Ophthalmological Society
• Society for Clinical and Translational Science